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Activation of Kir2.1 improves myocardial fibrosis by inhibiting Ca (2+) overload and the TGF-β1/Smad signaling pathway : Activation of Kir2.1 improves myocardial fibrosis
The inwardly rectifying potassium channel Kir2.1 is closely associated with many cardiovascular diseases. However, the effect and mechanism of Kir2.1 in diabetic cardiomyopathy remain unclear. In vivo, we use STZ to establish the model, and ventricular structural changes, myocardial inflammatory inf...
Autores principales: | Rong, Yi, Zhou, Xin, Guo, Zhenli, Zhang, Yingying, Qin, Wenjuan, Li, Li, Si, Junqiang, Yang, Rui, Li, Xinzhi, Ma, Ketao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281881/ https://www.ncbi.nlm.nih.gov/pubmed/37184279 http://dx.doi.org/10.3724/abbs.2023083 |
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