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Sex-specific effects of Cre expression in Syn1Cre mice

The Cre-loxP system has been used to generate cell-type specific mutations in mice, allowing researchers to investigate the underlying biological mechanisms of disease. However, the Cre-recombinase alone can induce phenotypes that confound comparisons among genotypes if the appropriate Cre control i...

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Detalles Bibliográficos
Autores principales: Baghdadi, Maarouf, Mesaros, Andrea, Purrio, Martin, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281999/
https://www.ncbi.nlm.nih.gov/pubmed/37340054
http://dx.doi.org/10.1038/s41598-023-37029-9