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Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells

Unconventional T cells, such as innate natural killer T cells (iNKT) cells, are an important part of vertebrate immune defences. iNKT recognise glycolipids through a T cell receptor (TCR) that is composed of a semi-invariant TCR α chain, paired with a restricted set of TCR β chains. Here, we show th...

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Detalles Bibliográficos
Autores principales: Iwanami, Norimasa, Richter, Andreas S., Sikora, Katarzyna, Boehm, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282035/
https://www.ncbi.nlm.nih.gov/pubmed/37339974
http://dx.doi.org/10.1038/s41467-023-39422-4