DIS3L2 knockdown impairs key oncogenic properties of colorectal cancer cells via the mTOR signaling pathway

DIS3L2 degrades different types of RNAs in an exosome-independent manner including mRNAs and several types of non-coding RNAs. DIS3L2-mediated degradation is preceded by the addition of nontemplated uridines at the 3’end of its targets by the terminal uridylyl transferases 4 and 7. Most of the liter...

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Detalles Bibliográficos
Autores principales: García-Moreno, Juan F., Lacerda, Rafaela, da Costa, Paulo J., Pereira, Marcelo, Gama-Carvalho, Margarida, Matos, Paulo, Romão, Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282049/
https://www.ncbi.nlm.nih.gov/pubmed/37340282
http://dx.doi.org/10.1007/s00018-023-04833-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282049/
https://www.ncbi.nlm.nih.gov/pubmed/37340282
http://dx.doi.org/10.1007/s00018-023-04833-5

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