Cargando…
DIS3L2 knockdown impairs key oncogenic properties of colorectal cancer cells via the mTOR signaling pathway
DIS3L2 degrades different types of RNAs in an exosome-independent manner including mRNAs and several types of non-coding RNAs. DIS3L2-mediated degradation is preceded by the addition of nontemplated uridines at the 3’end of its targets by the terminal uridylyl transferases 4 and 7. Most of the liter...
Autores principales: | García-Moreno, Juan F., Lacerda, Rafaela, da Costa, Paulo J., Pereira, Marcelo, Gama-Carvalho, Margarida, Matos, Paulo, Romão, Luísa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282049/ https://www.ncbi.nlm.nih.gov/pubmed/37340282 http://dx.doi.org/10.1007/s00018-023-04833-5 |
Ejemplares similares
-
Experimental supporting data on DIS3L2 over nonsense-mediated mRNA decay targets in human cells
por: da Costa, Paulo J., et al.
Publicado: (2019) -
Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition
por: Marques-Ramos, Ana, et al.
Publicado: (2017) -
Identification and Characterization of Two Novel Oncogenic mTOR Mutations
por: Murugan, Avaniyapuram Kannan, et al.
Publicado: (2019) -
Depdc5 knockdown causes mTOR‐dependent motor hyperactivity in zebrafish
por: de Calbiac, Hortense, et al.
Publicado: (2018) -
CMTM6 knockdown prevents glioma progression by inactivating the mTOR pathway
por: Wei, Li, et al.
Publicado: (2022)