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A novel specific aptamer targets cerebrovascular endothelial cells after ischemic stroke

Cell specific-targeted therapy (CSTT) for acute ischemic stroke remains underdeveloped. Cerebrovascular endothelial cells (CECs) are key components of the blood–brain barrier and are the first brain cells affected by ischemic stroke. After stroke, CEC injury causes insufficient energy supply to neur...

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Detalles Bibliográficos
Autores principales: Hu, Heng, Wu, Silin, Lee, Tae Jin, Gusdon, Aaron M., Liu, Yuxin, Choi, Huimahn A., Ren, Xuefang Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282052/
https://www.ncbi.nlm.nih.gov/pubmed/37339993
http://dx.doi.org/10.1038/s41598-023-36993-6