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Modelling ligand depletion for simultaneous affinity and binding site quantification on cells and tissue

The quantification of the number of targets in biological systems is an important parameter to assess the suitability of surface markers as targets for drugs, drug delivery and medical imaging. Likewise, quantifying the interaction with the target in terms of affinity and binding kinetics is essenti...

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Detalles Bibliográficos
Autores principales: Weber, Judith, Djurberg, Klara, Lundsten Salomonsson, Sara, Kamprath, Maria, Hoehne, Aileen, Westin, Hadis, Vergara, Fernanda, Bondza, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282064/
https://www.ncbi.nlm.nih.gov/pubmed/37340068
http://dx.doi.org/10.1038/s41598-023-37015-1