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Modelling ligand depletion for simultaneous affinity and binding site quantification on cells and tissue
The quantification of the number of targets in biological systems is an important parameter to assess the suitability of surface markers as targets for drugs, drug delivery and medical imaging. Likewise, quantifying the interaction with the target in terms of affinity and binding kinetics is essenti...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282064/ https://www.ncbi.nlm.nih.gov/pubmed/37340068 http://dx.doi.org/10.1038/s41598-023-37015-1 |