Design, synthesis, in vitro anti-α-glucosidase evaluations, and computational studies of new phthalimide-phenoxy-1,2,3-triazole-N-phenyl (or benzyl) acetamides as potential anti-diabetic agents

An important target in the treatment of type 2 diabetes is α-glucosidase. Inhibition of this enzyme led to delay in glucose absorption and decrease in postprandial hyperglycemia. A new series of phthalimide-phenoxy-1,2,3-triazole-N-phenyl (or benzyl) acetamides 11a–n were designed based on the repor...

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Detalles Bibliográficos
Autores principales: Emadi, Mehdi, Halimi, Mohammad, Moazzam, Ali, Hosseini, Samanesadat, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Ghadimi, Reza, Moghadamnia, Ali Akbar, Nasli-Esfahani, Ensieh, Mohammadi-Khanaposhtani, Maryam, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282079/
https://www.ncbi.nlm.nih.gov/pubmed/37340010
http://dx.doi.org/10.1038/s41598-023-36890-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282079/
https://www.ncbi.nlm.nih.gov/pubmed/37340010
http://dx.doi.org/10.1038/s41598-023-36890-y

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