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Integrated single-cell and bulk characterization of cuproptosis key regulator PDHB and association with tumor microenvironment infiltration in clear cell renal cell carcinoma

BACKGROUND: Renal clear cell carcinoma (ccRCC) is one of the most prevalent cancers worldwide. Accumulating evidence revealed that copper-induced cell death played a vital role in various tumors. However, the underlying mechanism of cuproptosis with molecular heterogeneity and tumor microenvironment...

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Detalles Bibliográficos
Autores principales: Wu, Jiajin, Wang, Songbo, Liu, Yiyang, Zhang, Tongtong, Wang, Xiaoyi, Miao, Chenkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282190/
https://www.ncbi.nlm.nih.gov/pubmed/37350959
http://dx.doi.org/10.3389/fimmu.2023.1132661