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Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming

BACKGROUND: A rat model of levodopa-induced dyskinesia (LID) showed enlarged axon terminals of striatal direct pathway neurons in the internal segment of the globus pallidus (GPi) with excessive gamma-aminobutyric acid (GABA) storage in them. Massive GABA release to GPi upon levodopa administration...

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Detalles Bibliográficos
Autores principales: Nakamura, Takashi, Nishijima, Haruo, Mori, Fumiaki, Kinoshita, Iku, Kon, Tomoya, Suzuki, Chieko, Wakabayashi, Koichi, Tomiyama, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282195/
https://www.ncbi.nlm.nih.gov/pubmed/37351424
http://dx.doi.org/10.3389/fnins.2023.1169336