Clec12a inhibits MSU-induced immune activation through lipid raft expulsion

Monosodium uric acid (MSU) crystal, the etiological agent of gout, has been shown to trigger innate immune responses via multiple pathways. It is known that MSU-induced lipid sorting on plasma membrane promotes the phosphorylation of Syk and eventually leads to the activation of phagocytes. However,...

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Detalles Bibliográficos
Autores principales: Xu, Ying, Song, Dingka, Wang, Wei, Li, Shixin, Yue, Tongtao, Xia, Tie, Shi, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282328/
https://www.ncbi.nlm.nih.gov/pubmed/37339805
http://dx.doi.org/10.26508/lsa.202301938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282328/
https://www.ncbi.nlm.nih.gov/pubmed/37339805
http://dx.doi.org/10.26508/lsa.202301938

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