The effect of cardioplegic supplementation with sildenafil on cardiac energetics in a piglet model of cardiopulmonary bypass and cardioplegic arrest with warm or cold cardioplegia

Cardioplegic cardioprotection strategies used during paediatric open-heart surgery remain suboptimal. Sildenafil, a phosphodiesterase 5 (PDE-5) inhibitor, has been shown to be cardioprotective against ischemia/reperfusion injury in a variety of experimental models and this study therefore tested the...

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Detalles Bibliográficos
Autores principales: Skeffington, Katie L., Mohamed Ahmed, Eltayeb, Rapetto, Filippo, Chanoit, Guillaume, Bond, Andrew R., Vardeu, Antonella, Ghorbel, Mohamed T., Suleiman, M-Saadeh, Caputo, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282544/
https://www.ncbi.nlm.nih.gov/pubmed/37351284
http://dx.doi.org/10.3389/fcvm.2023.1194645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282544/
https://www.ncbi.nlm.nih.gov/pubmed/37351284
http://dx.doi.org/10.3389/fcvm.2023.1194645

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