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Mitochondrial ROS and base excision repair steps leading to DNA nick formation drive ultraviolet induced-NETosis
Reactive oxygen species (ROS) is essential for neutrophil extracellular trap formation (NETosis), and generated either by NADPH oxidases (e.g., during infections) or mitochondria (e.g., sterile injury) in neutrophils. We recently showed that ultraviolet (UV) radiation, a sterile injury-inducing agen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282603/ https://www.ncbi.nlm.nih.gov/pubmed/37350954 http://dx.doi.org/10.3389/fimmu.2023.1198716 |