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Mitochondrial ROS and base excision repair steps leading to DNA nick formation drive ultraviolet induced-NETosis

Reactive oxygen species (ROS) is essential for neutrophil extracellular trap formation (NETosis), and generated either by NADPH oxidases (e.g., during infections) or mitochondria (e.g., sterile injury) in neutrophils. We recently showed that ultraviolet (UV) radiation, a sterile injury-inducing agen...

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Detalles Bibliográficos
Autores principales: Azzouz, Dhia, Palaniyar, Nades
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282603/
https://www.ncbi.nlm.nih.gov/pubmed/37350954
http://dx.doi.org/10.3389/fimmu.2023.1198716