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Incorporating lesion-to-lesion heterogeneity into early oncology decision making

RECISTv1.1 (Response Evaluation Criteria In Solid Tumors) is the most commonly used response grading criteria in early oncology trials. In this perspective, we argue that RECISTv1.1 is ambiguous regarding lesion-to-lesion variation that can introduce bias in decision making. We show theoretical exam...

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Detalles Bibliográficos
Autores principales: Kumar, Rukmini, Qi, Timothy, Cao, Yanguang, Topp, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282604/
https://www.ncbi.nlm.nih.gov/pubmed/37350966
http://dx.doi.org/10.3389/fimmu.2023.1173546