Pyrrolo[2,3-e]indazole as a novel chemotype for both influenza A virus and pneumococcal neuraminidase inhibitors

Influenza infections are often exacerbated by secondary bacterial infections, primarily caused by Streptococcus pneumoniae. Both respiratory pathogens have neuraminidases that support infection. Therefore, we hypothesized that dual inhibitors of viral and bacterial neuraminidases might be an advanta...

Descripción completa

Detalles Bibliográficos
Autores principales: Egorova, Anna, Richter, Martina, Khrenova, Maria, Dietrich, Elisabeth, Tsedilin, Andrey, Kazakova, Elena, Lepioshkin, Alexander, Jahn, Birgit, Chernyshev, Vladimir, Schmidtke, Michaela, Makarov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282731/
https://www.ncbi.nlm.nih.gov/pubmed/37350858
http://dx.doi.org/10.1039/d3ra02895j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10282731/
https://www.ncbi.nlm.nih.gov/pubmed/37350858
http://dx.doi.org/10.1039/d3ra02895j

Ejemplares similares