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Structure–Activity Relationship of Lower Chlorinated Biphenyls and Their Human-Relevant Metabolites for Astrocyte Toxicity

[Image: see text] Exposure to polychlorinated biphenyls (PCBs) is associated with developmental neurotoxicity and neurodegenerative disorders; however, the underlying mechanisms of pathogenesis are unknown. Existing literature has focused mainly on using neurons as a model system to study mechanisms...

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Detalles Bibliográficos
Autores principales: Paranjape, Neha, Dean, Laura E., Martinez, Andres, Tjalkens, Ronald B., Lehmler, Hans-Joachim, Doorn, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283044/
https://www.ncbi.nlm.nih.gov/pubmed/37279407
http://dx.doi.org/10.1021/acs.chemrestox.3c00095