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Modulation of transcription burst amplitude underpins dosage compensation in the Drosophila embryo

Dosage compensation, the balancing of X-linked gene expression between sexes and to the autosomes, is critical to an organism’s fitness and survival. In Drosophila, dosage compensation involves hypertranscription of the male X chromosome. Here, we use quantitative live imaging and modeling at single...

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Detalles Bibliográficos
Autores principales: Forbes Beadle, Lauren, Zhou, Hongpeng, Rattray, Magnus, Ashe, Hilary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283159/
https://www.ncbi.nlm.nih.gov/pubmed/37060568
http://dx.doi.org/10.1016/j.celrep.2023.112382