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Gene editing with ‘pencil’ rather than ‘scissors’ in human pluripotent stem cells
Owing to the advances in genome editing technologies, research on human pluripotent stem cells (hPSCs) have recently undergone breakthroughs that enable precise alteration of desired nucleotide bases in hPSCs for the creation of isogenic disease models or for autologous ex vivo cell therapy. As path...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283231/ https://www.ncbi.nlm.nih.gov/pubmed/37340491 http://dx.doi.org/10.1186/s13287-023-03394-5 |