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Gene editing with ‘pencil’ rather than ‘scissors’ in human pluripotent stem cells

Owing to the advances in genome editing technologies, research on human pluripotent stem cells (hPSCs) have recently undergone breakthroughs that enable precise alteration of desired nucleotide bases in hPSCs for the creation of isogenic disease models or for autologous ex vivo cell therapy. As path...

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Detalles Bibliográficos
Autores principales: Park, Ju-Chan, Park, Mihn Jeong, Lee, Seung-Yeon, Kim, Dayeon, Kim, Keun-Tae, Jang, Hyeon-Ki, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283231/
https://www.ncbi.nlm.nih.gov/pubmed/37340491
http://dx.doi.org/10.1186/s13287-023-03394-5