CNETML: maximum likelihood inference of phylogeny from copy number profiles of multiple samples

Phylogenetic trees based on copy number profiles from multiple samples of a patient are helpful to understand cancer evolution. Here, we develop a new maximum likelihood method, CNETML, to infer phylogenies from such data. CNETML is the first program to jointly infer the tree topology, node ages, an...

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Detalles Bibliográficos
Autores principales: Lu, Bingxin, Curtius, Kit, Graham, Trevor A., Yang, Ziheng, Barnes, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283241/
https://www.ncbi.nlm.nih.gov/pubmed/37340508
http://dx.doi.org/10.1186/s13059-023-02983-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283241/
https://www.ncbi.nlm.nih.gov/pubmed/37340508
http://dx.doi.org/10.1186/s13059-023-02983-0

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