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CNETML: maximum likelihood inference of phylogeny from copy number profiles of multiple samples
Phylogenetic trees based on copy number profiles from multiple samples of a patient are helpful to understand cancer evolution. Here, we develop a new maximum likelihood method, CNETML, to infer phylogenies from such data. CNETML is the first program to jointly infer the tree topology, node ages, an...
Autores principales: | Lu, Bingxin, Curtius, Kit, Graham, Trevor A., Yang, Ziheng, Barnes, Chris P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283241/ https://www.ncbi.nlm.nih.gov/pubmed/37340508 http://dx.doi.org/10.1186/s13059-023-02983-0 |
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