Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of extracellular matrix in the pulmonary interstitium and progressive functional decline. We hypothesized that integration of multi-omics data would identify clinically meaningful molecular endotypes of IPF. METHODS...

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Detalles Bibliográficos
Autores principales: Ruan, Peifeng, Todd, Jamie L, Zhao, Hongyu, Liu, Yi, Vinisko, Richard, Soellner, Julia F., Schmid, Ramona, Kaner, Robert J., Luckhardt, Tracy R., Neely, Megan L., Noth, Imre, Porteous, Mary, Raj, Rishi, Safdar, Zeenat, Strek, Mary E, Hesslinger, Christian, Palmer, Scott M., Leonard, Thomas B., Salisbury, Margaret L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283254/
https://www.ncbi.nlm.nih.gov/pubmed/37344825
http://dx.doi.org/10.1186/s12931-023-02435-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283254/
https://www.ncbi.nlm.nih.gov/pubmed/37344825
http://dx.doi.org/10.1186/s12931-023-02435-0

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