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METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinoma

BACKGROUND: N6-methyladenosine (m6A) is associated with mammalian mRNA biogenesis, decay, translation and metabolism, and also contributes greatly to gastrointestinal tumor formation and development. Therefore, the specific mechanisms and signaling pathways mediated by methyltransferase-like 3 (METT...

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Detalles Bibliográficos
Autores principales: Zhang, Zhijin, Fu, Jun, Zhang, Yuhao, Qin, Xianju, Wang, Yuexia, Xing, Chungen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283274/
https://www.ncbi.nlm.nih.gov/pubmed/37344779
http://dx.doi.org/10.1186/s12876-023-02844-x