Cargando…

Generation, evolution, interfering factors, applications, and challenges of patient-derived xenograft models in immunodeficient mice

Establishing appropriate preclinical models is essential for cancer research. Evidence suggests that cancer is a highly heterogeneous disease. This follows the growing use of cancer models in cancer research to avoid these differences between xenograft tumor models and patient tumors. In recent year...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Mingtang, Ruan, Zijing, Tang, Jiaxi, Liu, Maozhu, Hu, Chengji, Fan, Ping, Dai, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283277/
https://www.ncbi.nlm.nih.gov/pubmed/37344821
http://dx.doi.org/10.1186/s12935-023-02953-3