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Generation, evolution, interfering factors, applications, and challenges of patient-derived xenograft models in immunodeficient mice
Establishing appropriate preclinical models is essential for cancer research. Evidence suggests that cancer is a highly heterogeneous disease. This follows the growing use of cancer models in cancer research to avoid these differences between xenograft tumor models and patient tumors. In recent year...
Autores principales: | Zeng, Mingtang, Ruan, Zijing, Tang, Jiaxi, Liu, Maozhu, Hu, Chengji, Fan, Ping, Dai, Xinhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283277/ https://www.ncbi.nlm.nih.gov/pubmed/37344821 http://dx.doi.org/10.1186/s12935-023-02953-3 |
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