Blockage of autophagosome-lysosome fusion through SNAP29 O-GlcNAcylation promotes apoptosis via ROS production

Macroautophagy/autophagy has been shown to exert a dual role in cancer i.e., promoting cell survival or cell death depending on the cellular context and the cancer stage. Therefore, development of potent autophagy modulators, with a clear mechanistic understanding of their target action, has paramou...

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Detalles Bibliográficos
Autores principales: Pellegrini, Francesca Romana, De Martino, Sara, Fianco, Giulia, Ventura, Irene, Valente, Davide, Fiore, Mario, Trisciuoglio, Daniela, Degrassi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283446/
https://www.ncbi.nlm.nih.gov/pubmed/36704963
http://dx.doi.org/10.1080/15548627.2023.2170962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10283446/
https://www.ncbi.nlm.nih.gov/pubmed/36704963
http://dx.doi.org/10.1080/15548627.2023.2170962

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