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Colorectal cancer in patients of advanced age is associated with increased incidence of BRAF p.V600E mutation and mismatch repair deficiency

INTRODUCTION: The highest incidence of colorectal cancer (CRC) is in patients diagnosed at 80 years or older highlighting a need for understanding the clinical and molecular features of these tumors. Methods. In this retrospective cohort study, 544 CRCs underwent next generation sequencing and misma...

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Detalles Bibliográficos
Autores principales: Christenson, Eric S., Tsai, Hua-Ling, Le, Dung T., Jaffee, Elizabeth M., Dudley, Jonathan, Xian, Rena R., Gocke, Christopher D., Eshleman, James R., Lin, Ming-Tseh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284017/
https://www.ncbi.nlm.nih.gov/pubmed/37350948
http://dx.doi.org/10.3389/fonc.2023.1193259