Tracking the mechanism of covalent molecular glue stabilization using native mass spectrometry

Molecular glues are powerful tools for the control of protein–protein interactions. Yet, the mechanisms underlying multi-component protein complex formation remain poorly understood. Native mass spectrometry (MS) detects multiple protein species simultaneously, providing an entry to elucidate these...

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Detalles Bibliográficos
Autores principales: Verhoef, Carlo J. A., Kay, Danielle F., van Dijck, Lars, Doveston, Richard G., Brunsveld, Luc, Leney, Aneika C., Cossar, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284121/
https://www.ncbi.nlm.nih.gov/pubmed/37350830
http://dx.doi.org/10.1039/d3sc01732j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284121/
https://www.ncbi.nlm.nih.gov/pubmed/37350830
http://dx.doi.org/10.1039/d3sc01732j

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