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Evaluating the Contribution of Cell Type–Specific Alternative Splicing to Variation in Lipid Levels
Genome-wide association studies have identified hundreds of loci associated with lipid levels. However, the genetic mechanisms underlying most of these loci are not well-understood. Recent work indicates that changes in the abundance of alternatively spliced transcripts contribute to complex trait v...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284136/ https://www.ncbi.nlm.nih.gov/pubmed/37165871 http://dx.doi.org/10.1161/CIRCGEN.120.003249 |