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Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection

Innate immune responses are crucial for limiting virus infection. However, viruses often hijack our best defenses for viral objectives. Human Cytomegalovirus (HCMV) is a beta herpesvirus which establishes a life-long latent infection. Defining the virus-host interactions controlling latency and reac...

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Detalles Bibliográficos
Autores principales: Zarrella, Kristen, Longmire, Pierce, Zeltzer, Sebastian, Collins-McMillen, Donna, Hancock, Meaghan, Buehler, Jason, Reitsma, Justin M., Terhune, Scott S., Nelson, Jay A., Goodrum, Felicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284425/
https://www.ncbi.nlm.nih.gov/pubmed/37289831
http://dx.doi.org/10.1371/journal.ppat.1011185