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A molecular optomechanics approach reveals functional relevance of force transduction across talin and desmoplakin

Many mechanobiological processes that govern development and tissue homeostasis are regulated on the level of individual molecular linkages, and a number of proteins experiencing piconewton-scale forces in cells have been identified. However, under which conditions these force-bearing linkages becom...

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Detalles Bibliográficos
Autores principales: Sadhanasatish, Tanmay, Augustin, Katharina, Windgasse, Lukas, Chrostek-Grashoff, Anna, Rief, Matthias, Grashoff, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284548/
https://www.ncbi.nlm.nih.gov/pubmed/37343090
http://dx.doi.org/10.1126/sciadv.adg3347