H/ACA snRNP–dependent ribosome biogenesis regulates translation of polyglutamine proteins

Stem cells in many systems, including Drosophila germline stem cells (GSCs), increase ribosome biogenesis and translation during terminal differentiation. Here, we show that the H/ACA small nuclear ribonucleoprotein (snRNP) complex that promotes pseudouridylation of ribosomal RNA (rRNA) and ribosome...

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Detalles Bibliográficos
Autores principales: Breznak, Shane M., Peng, Yingshi, Deng, Limin, Kotb, Noor M., Flamholz, Zachary, Rapisarda, Ian T., Martin, Elliot T., LaBarge, Kara A., Fabris, Dan, Gavis, Elizabeth R., Rangan, Prashanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284551/
https://www.ncbi.nlm.nih.gov/pubmed/37343092
http://dx.doi.org/10.1126/sciadv.ade5492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284551/
https://www.ncbi.nlm.nih.gov/pubmed/37343092
http://dx.doi.org/10.1126/sciadv.ade5492

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