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Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line

Unlike single-gene mutations leading to Mendelian conditions, common human diseases are likely to be emergent phenomena arising from multilayer, multiscale, and highly interconnected interactions. Atrial and ventricular septal defects are the most common forms of cardiac congenital anomalies in huma...

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Detalles Bibliográficos
Autores principales: Moradi Marjaneh, Mahdi, Kirk, Edwin P, Patrick, Ralph, Alankarage, Dimuthu, Humphreys, David T, Del Monte-Nieto, Gonzalo, Cornejo-Paramo, Paola, Janbandhu, Vaibhao, Doan, Tram B, Dunwoodie, Sally L, Wong, Emily S, Moran, Chris, Martin, Ian CA, Thomson, Peter C, Harvey, Richard P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284603/
https://www.ncbi.nlm.nih.gov/pubmed/37272612
http://dx.doi.org/10.7554/eLife.83606