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GRETTA: an R package for mapping in silico genetic interaction and essentiality networks

SUMMARY: Mapping genetic interactions and essentiality networks in human cell lines has been used to identify vulnerabilities of cells carrying specific genetic alterations and to associate novel functions to genes, respectively. In vitro and in vivo genetic screens to decipher these networks are re...

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Detalles Bibliográficos
Autores principales: Takemon, Yuka, Marra, Marco A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284671/
https://www.ncbi.nlm.nih.gov/pubmed/37326978
http://dx.doi.org/10.1093/bioinformatics/btad381