The role of leukotriene inhibition using a 5-lipoxygenase (5-LO) inhibitor in a joint contracture model

PURPOSE: Arthrofibrosis is a common inflammatory complication of joint trauma and surgery. 5lipoxygenase (5-LO) is a key enzyme involved in inflammation. Inhibition of 5-LO has been shown to reduce inflammation in heart and lung models but has not been examined in a joint contracture model. METHODS:...

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Detalles Bibliográficos
Autores principales: Jeffs, Alexander D., Boyd, Michael, Larabee, Landon, Shelton, Matthew, Bassil, Alexander, Taylor, Ross, Berkoff, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284778/
https://www.ncbi.nlm.nih.gov/pubmed/37341811
http://dx.doi.org/10.1186/s40634-023-00616-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284778/
https://www.ncbi.nlm.nih.gov/pubmed/37341811
http://dx.doi.org/10.1186/s40634-023-00616-w

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