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The role of leukotriene inhibition using a 5-lipoxygenase (5-LO) inhibitor in a joint contracture model
PURPOSE: Arthrofibrosis is a common inflammatory complication of joint trauma and surgery. 5lipoxygenase (5-LO) is a key enzyme involved in inflammation. Inhibition of 5-LO has been shown to reduce inflammation in heart and lung models but has not been examined in a joint contracture model. METHODS:...
Autores principales: | Jeffs, Alexander D., Boyd, Michael, Larabee, Landon, Shelton, Matthew, Bassil, Alexander, Taylor, Ross, Berkoff, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284778/ https://www.ncbi.nlm.nih.gov/pubmed/37341811 http://dx.doi.org/10.1186/s40634-023-00616-w |
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