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Joint inference of exclusivity patterns and recurrent trajectories from tumor mutation trees

Cancer progression is an evolutionary process shaped by both deterministic and stochastic forces. Multi-region and single-cell sequencing of tumors enable high-resolution reconstruction of the mutational history of each tumor and highlight the extensive diversity across tumors and patients. Resolvin...

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Detalles Bibliográficos
Autores principales: Luo, Xiang Ge, Kuipers, Jack, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284838/
https://www.ncbi.nlm.nih.gov/pubmed/37344522
http://dx.doi.org/10.1038/s41467-023-39400-w