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In silico mutagenesis-based designing of oncogenic SHP2 peptide to inhibit cancer progression

Cancer is among the top causes of death, accounting for an estimated 9.6 million deaths in 2018, it appeared that approximately 500,000 people die from cancer in the United States alone annually. The SHP2 plays a major role in regulation of cell growth, proliferation, and differentiation, and functi...

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Detalles Bibliográficos
Autores principales: Shahab, Muhammad, Khan, Shahin Shah, Zulfat, Maryam, Bin Jardan, Yousef A., Mekonnen, Amare Bitew, Bourhia, Mohammed, Zheng, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284847/
https://www.ncbi.nlm.nih.gov/pubmed/37344519
http://dx.doi.org/10.1038/s41598-023-37020-4