Structural basis of protein condensation on microtubules underlying branching microtubule nucleation

Targeting protein for Xklp2 (TPX2) is a key factor that stimulates branching microtubule nucleation during cell division. Upon binding to microtubules (MTs), TPX2 forms condensates via liquid-liquid phase separation, which facilitates recruitment of microtubule nucleation factors and tubulin. We rep...

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Detalles Bibliográficos
Autores principales: Guo, Changmiao, Alfaro-Aco, Raymundo, Zhang, Chunting, Russell, Ryan W., Petry, Sabine, Polenova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284871/
https://www.ncbi.nlm.nih.gov/pubmed/37344496
http://dx.doi.org/10.1038/s41467-023-39176-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284871/
https://www.ncbi.nlm.nih.gov/pubmed/37344496
http://dx.doi.org/10.1038/s41467-023-39176-z

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