Parahydrogen-induced polarization enables the single-scan NMR detection of a 236 kDa biopolymer at nanomolar concentrations

Nuclear magnetic resonance (NMR) experiments utilizing parahydrogen-induced polarization (PHIP) were performed to elucidate the PHIP activity of the synthetic 236 kDa biopolymer poly-γ-(4-propargyloxy)-benzyl-L-glutamate) (PPOBLG). The homopolypeptide was successfully hyperpolarized and the enhanced...

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Detalles Bibliográficos
Autores principales: Theiss, Franziska, Wienands, Laura, Lins, Jonas, Alcaraz-Janßen, Marcel, Thiele, Christina M., Buntkowsky, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284874/
https://www.ncbi.nlm.nih.gov/pubmed/37344547
http://dx.doi.org/10.1038/s41598-023-37202-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284874/
https://www.ncbi.nlm.nih.gov/pubmed/37344547
http://dx.doi.org/10.1038/s41598-023-37202-0

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