Tagmentation-based analysis reveals the clonal behavior of CAR-T cells in association with lentivector integration sites

Integration site (IS) analysis is essential in ensuring safety and efficacy of gene therapies when integrating vectors are used. Although clinical trials of gene therapy are rapidly increasing, current methods have limited use in clinical settings because of their lengthy protocols. Here, we describ...

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Detalles Bibliográficos
Autores principales: Kim, Jaeryuk, Park, Miyoung, Baek, Gyungwon, Kim, Joo-Il, Kwon, Euna, Kang, Byeong-Cheol, Kim, Jong-Il, Kang, Hyoung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285042/
https://www.ncbi.nlm.nih.gov/pubmed/37360944
http://dx.doi.org/10.1016/j.omto.2023.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285042/
https://www.ncbi.nlm.nih.gov/pubmed/37360944
http://dx.doi.org/10.1016/j.omto.2023.05.004

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