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Tagmentation-based analysis reveals the clonal behavior of CAR-T cells in association with lentivector integration sites
Integration site (IS) analysis is essential in ensuring safety and efficacy of gene therapies when integrating vectors are used. Although clinical trials of gene therapy are rapidly increasing, current methods have limited use in clinical settings because of their lengthy protocols. Here, we describ...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285042/ https://www.ncbi.nlm.nih.gov/pubmed/37360944 http://dx.doi.org/10.1016/j.omto.2023.05.004 |