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Cavin-2 loss exacerbates hypoxia-induced pulmonary hypertension with excessive eNOS phosphorylation and protein nitration

Pulmonary hypertension (PH) is associated with a poor prognosis even in recent years. Caveolin-1 (CAV1), a caveolae-associated protein, is a causal gene in PH. Cavin-2, one of the other caveolae-associated proteins, forms protein complexes with CAV1 and influences each other's functions. Howeve...

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Detalles Bibliográficos
Autores principales: Kasahara, Takeru, Ogata, Takehiro, Nakanishi, Naohiko, Tomita, Shinya, Higuchi, Yusuke, Maruyama, Naoki, Hamaoka, Tetsuro, Matoba, Satoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285171/
https://www.ncbi.nlm.nih.gov/pubmed/37360100
http://dx.doi.org/10.1016/j.heliyon.2023.e17193