Identification of IKZF1 genetic mutations as new molecular subtypes in acute myeloid leukaemia

BACKGROUND: Genetic mutations of IKZF1 have been frequently delineated in B‐lineage acute leukaemia (B‐ALL) but rarely elucidated in acute myeloid leukaemia (AML). IKZF1 mutations confer a poor prognosis in AML, and hotspot mutations of IKZF1, N159Y and N159S tend to occur in B‐ALL and AML respectiv...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Cheng, Wenyan, Zhang, Yvyin, Zhang, Yuliang, Sun, Tengfei, Zhu, Yongmei, Yin, Wei, Zhang, Jianan, Li, Jianfeng, Shen, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285267/
https://www.ncbi.nlm.nih.gov/pubmed/37345307
http://dx.doi.org/10.1002/ctm2.1309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285267/
https://www.ncbi.nlm.nih.gov/pubmed/37345307
http://dx.doi.org/10.1002/ctm2.1309

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