Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance

BACKGROUND & AIMS: Lipotoxicity triggers non-alcoholic fatty liver disease (NAFLD) progression owing to the accumulation of toxic lipids in hepatocytes including saturated fatty acids (SFAs), which activate pro-inflammatory pathways. We investigated the impact of hepatocyte- or circulating-deriv...

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Detalles Bibliográficos
Autores principales: Garcia-Martinez, Irma, Alen, Rosa, Pereira, Laura, Povo-Retana, Adrián, Astudillo, Alma M., Hitos, Ana B., Gomez-Hurtado, Isabel, Lopez-Collazo, Eduardo, Boscá, Lisardo, Francés, Rubén, Lizasoain, Ignacio, Moro, María Ángeles, Balsinde, Jesús, Izquierdo, Manuel, Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285285/
https://www.ncbi.nlm.nih.gov/pubmed/37360906
http://dx.doi.org/10.1016/j.jhepr.2023.100756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285285/
https://www.ncbi.nlm.nih.gov/pubmed/37360906
http://dx.doi.org/10.1016/j.jhepr.2023.100756

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