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The impact of CYP2C19 genotype on phenoconversion by concomitant medication

Introduction: Pharmacogenetics-informed drug prescribing is increasingly applied in clinical practice. Typically, drug metabolizing phenotypes are determined based on genetic test results, whereupon dosage or drugs are adjusted. Drug-drug-interactions (DDIs) caused by concomitant medication can howe...

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Detalles Bibliográficos
Autores principales: de Jong, Laura M., Boussallami, Soukayna, Sánchez-López, Elena, Giera, Martin, Tushuizen, Maarten E., Hoekstra, Menno, Hawinkels, Lukas J. A. C., Rissmann, Robert, Swen, Jesse J., Manson, Martijn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285291/
https://www.ncbi.nlm.nih.gov/pubmed/37361233
http://dx.doi.org/10.3389/fphar.2023.1201906