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The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease

Introduction: Profibrotic phenotype of renal tubular epithelial cells (TECs) featured with epithelial to mesenchymal transition (EMT) and profibrotic factors secretion, and aberrant accumulation of CD206( + ) M2 macrophages are the key points in the transition from acute kidney injury (AKI) to chron...

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Detalles Bibliográficos
Autores principales: Shu, Huapan, Wang, Yumei, Zhang, Hui, Dong, Qingqing, Sun, Lulu, Tu, Yuchi, Liao, Qianqian, Feng, Li, Yao, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285316/
https://www.ncbi.nlm.nih.gov/pubmed/37361201
http://dx.doi.org/10.3389/fphar.2023.1169054