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The double-hit protocol induces HFpEF and impairs myocardial ubiquitin-proteasome system performance in FVB/N mice

Heart failure with preserved ejection fraction (HFpEF) is a leading cause of death and disability, with its prevalence surpassing that of heart failure with reduced ejection fraction. Obesity and hypertension are often associated with HFpEF. HFpEF can be modeled through simultaneous metabolic and hy...

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Detalles Bibliográficos
Autores principales: Lira, Jose R., Guymon, Andrew L., Yang, Liuqing, Sternburg, Jack O., Giri, Samiksha, Wang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285383/
https://www.ncbi.nlm.nih.gov/pubmed/37362441
http://dx.doi.org/10.3389/fphys.2023.1208153