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IgGFc-binding protein and MUC2 mucin produced by colonic goblet-like cells spatially interact non-covalently and regulate wound healing

The colonic mucus bilayer is the first line of innate host defense that at the same time houses and nourishes the commensal microbiota. The major components of mucus secreted by goblet cells are MUC2 mucin and the mucus-associated protein, FCGBP (IgGFc-binding protein). In this study, we determine i...

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Detalles Bibliográficos
Autores principales: Gorman, Hayley, Moreau, France, Dufour, Antoine, Chadee, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285406/
https://www.ncbi.nlm.nih.gov/pubmed/37359538
http://dx.doi.org/10.3389/fimmu.2023.1211336