Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss

Maternal uterine remodeling facilitates embryo implantation, stromal cell decidualization and placentation, and perturbation of these processes may cause pregnancy loss. Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that epigenetically represses gene transcription; loss of uterin...

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Detalles Bibliográficos
Autores principales: Sirohi, Vijay K., Medrano, Theresa I., Kannan, Athilakshmi, Bagchi, Indrani C., Cooke, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
https://www.ncbi.nlm.nih.gov/pubmed/37360688
http://dx.doi.org/10.1016/j.isci.2023.107028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
https://www.ncbi.nlm.nih.gov/pubmed/37360688
http://dx.doi.org/10.1016/j.isci.2023.107028

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